Male breast cancer: a review

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Male breast cancer: a review

Male breast cancer (MBC) is rare, with the peak age of onset at 71 years. BRCA2 mutations are more frequent than BRCA1 with 20% of cases giving a family history. Risk factors for MBC are poorly understood and include working in high-ambient temperatures and exhaust fume exposure. MBC is associated with hyperoestrogenic states found in liver disease, Klinefelter's syndrome, gonadal dysfunction o...

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Male Breast Cancer; A Review of Risk Factors and Clinical and Radiological Features

While male breast cancer (MBC) consists only 1% of all breast cancers in the United States, approximately 2000 men are diagnosed annually and the incidence seems to be slowly increasing. About 50% of men have axillary nodal metastasis at the time of diagnosis. A mean delay of 6 to 10 months occurs in the diagnosis of MBC, which leads to the progression of the disease before presentation. More t...

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Male Breast Cancer; A Review of Risk Factors and Clinical and Radiological Features

While male breast cancer (MBC) consists only 1% of all breast cancers in the United States, approximately 2000 men are diagnosed annually and the incidence seems to be slowly increasing. About 50% of men have axillary nodal metastasis at the time of diagnosis. A mean delay of 6 to 10 months occurs in the diagnosis of MBC, which leads to the progression of the disease before presentation. More t...

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Male Breast Cancer and Hyperestrogenemia: A Thirteen-Year Review

Background Male breast cancer (MBC) is a very rare malignancy and accounts for 0.1% of all male cancers. MBC has not been studied as extensively as its female counterpart. Certain clinical and pathological risk factors like smoking history, age at onset, family history of cancer, obesity, ethnicity, estrogen/progesterone receptor status and BRCA gene mutation status have all been studied well i...

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Understanding and management of male breast cancer: a critical review.

Breast cancer is a rare disease in men representing nearly 1% of the total breast cancer cases worldwide. While treatments developed for women with breast cancer are often applied to treat men with breast cancer, however, lack of awareness of this disease leads to its detection at a later stage in men. This review discusses male breast cancer and draws comparisons with female breast cancer and ...

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ژورنال

عنوان ژورنال: Cancer Treatment Reviews

سال: 1976

ISSN: 0305-7372

DOI: 10.1016/s0305-7372(76)80006-0